Leo Wan

Leo Wan

Professor, Biomedical Engineering

Research Expertise
BioMEMS, organ-on-a-Chip, tissue engineering, cell chirality
Research

We use microfabrication to make biological tissues and plan to stimulate cardiac tissues with microsize electrodes.

Publications

G Dai, AW Feinberg and LQ Wan*, 2021. Recent Advances in Cellular and Molecular Bioengineering for Building and Translation of Biological Systems. Cellular and Molecular Bioengineering, 14(4): 1-16.

P Ray, AS Chin, KE Worley, J Fan, G Kuar, M Wu, and LQ Wan*, Intrinsic Cell Chirality Regulate Left-Right Symmetry Breaking During Cardiac Looping, Proceedings of National Academy of Sciences, pii: 201808052. https://doi.org/10.1073/pnas.1808052115.

AS Chin, KE Worley, P Ray, G Kuar, J Fan, and LQ Wan*, Cell Chirality Revealed By Three-Dimensional Spontaneous Rotation, Proceedings of National Academy of Sciences, 115(18), pp.12188-12193, https://doi.org/10.1073/pnas.1805932115.

LQ Wan, K Ronaldson, M Park, G Taylor, Y Zhang, JM Gimble, and G Vunjak-Novakovic, 2011. Micropatterned Mammalian Cells Exhibit Phenotype-Specific Left-Right Asymmetry, Proceedings of National Academy of Science, 108(30), pp. 12295-300

J. Fan, P Ray, Y Lu, G Kaur, JJ Schwarz, and LQ Wan*, 2018. Cell chirality regulates intercellular junctions and endothelial permeability. Science Advances, 4, eaat2111. https://doi.org/ 10.1126/sciadv.aat2111.

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